Podcst

How 'boosting' your immune system increases inflammation and 4 ways to support balance instead | Dr Giulia Enders

ZOE Science & Nutrition

ZOE

May 7, 2026

Show Notes

What if boosting your immune system is the wrong goal?

Today, Dr Giulia Enders explains how boosting immunity may increase inflammation and why your symptoms are often part of your body’s defence. Your immune system is not failing when you feel sick. It is trying to protect you. So what should you focus on instead?

That’s the idea at the very heart of Giulia’s new book, Organ Speak. Giulia is a gastroenterologist and author whose previous book, Gut, sold eight million copies and helped convince the world that gut health was worth taking seriously.

She explains how the immune system really works and why symptoms like a runny nose, cough, or fever come from your body, not the infection itself. You’ll learn how sugar may push the immune system toward inflammation, how stress can weaken it, and why sleep is key for producing immune cells. This episode also explores how exercise helps regulate your immune response. The core idea is simple: health is not about making your immune system stronger. It is about keeping it balanced.

By the end of this episode, you will have practical ways to support that balance and habits to help your immune system respond in the right way.

If the sneezing, runny nose, fever - all of it - are actually the whole point, how much energy should you spend in suppressing them?

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Timecodes

Intro

Why being sick feels like failure

The problem with only treating the gut

Why your body is not broken

When your immune system gets overprotective

The virus may not cause your symptoms

Should you stop cold symptoms?

When diarrhoea medicine can backfire

Should you take painkillers when sick?

Why immunity is not a war

The invisible microbe cloak protecting you

How your body clears bacteria from skin

Your microbiome is part of immunity

Is your immune system like AI?

Why boosting immunity can go wrong

Are immune supplements worth taking?

How stress weakens your gut barrier

The one-minute breathing reset

Why sleep builds immune cells

The most important half of sleep

Do naps help your immune system?

What to eat for immune balance

How exercise moves immune cells

Why exercise when sick can be risky

Strength vs cardio for immunity

The immune system takeaway everyone needs


📚Books by our ZOE Scientists

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

Food For Life by Prof. Tim Spector

Ferment by Prof. Tim Spector

Good Mood Food (preorder) by Prof. Tim Spector


Free resources from ZOE

The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra

Eating for Better Brain Health: Your brain-gut blueprint

Howto eat in 2026- Discover ZOE’s 8 nutrition principles for long-term health

Live Healthier: Top 10 Tips From ZOE Science & Nutrition

Gut Guide - For a Healthier Microbiome in Weeks

Better Breakfast Guide


Mentioned in today's episode

Organ Speak: What it really means to listen to our bodies by Giulia Enders

Gut by Giulia Enders

Associationof Stress-Related Disorders With Autoimmune Disease, JAMA (2018)

Sugar-sweetenedsoda consumption and risk of developing rheumatoid arthritis, AJCN (2014)


Have feedback or a topic you'd like us to cover? Let us know here.

Episode transcripts are available here.


How 'boosting' your immune system increases inflammation and 4 ways to support balance instead | Dr Giulia Enders — Podcst