
Show Notes
What if boosting your immune system is the wrong goal?
Today, Dr Giulia Enders explains how boosting immunity may increase inflammation and why your symptoms are often part of your body’s defence. Your immune system is not failing when you feel sick. It is trying to protect you. So what should you focus on instead?
That’s the idea at the very heart of Giulia’s new book, Organ Speak. Giulia is a gastroenterologist and author whose previous book, Gut, sold eight million copies and helped convince the world that gut health was worth taking seriously.
She explains how the immune system really works and why symptoms like a runny nose, cough, or fever come from your body, not the infection itself. You’ll learn how sugar may push the immune system toward inflammation, how stress can weaken it, and why sleep is key for producing immune cells. This episode also explores how exercise helps regulate your immune response. The core idea is simple: health is not about making your immune system stronger. It is about keeping it balanced.
By the end of this episode, you will have practical ways to support that balance and habits to help your immune system respond in the right way.
If the sneezing, runny nose, fever - all of it - are actually the whole point, how much energy should you spend in suppressing them?
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Timecodes
Intro
Why being sick feels like failure
The problem with only treating the gut
Why your body is not broken
When your immune system gets overprotective
The virus may not cause your symptoms
Should you stop cold symptoms?
When diarrhoea medicine can backfire
Should you take painkillers when sick?
Why immunity is not a war
The invisible microbe cloak protecting you
How your body clears bacteria from skin
Your microbiome is part of immunity
Is your immune system like AI?
Why boosting immunity can go wrong
Are immune supplements worth taking?
How stress weakens your gut barrier
The one-minute breathing reset
Why sleep builds immune cells
The most important half of sleep
Do naps help your immune system?
What to eat for immune balance
How exercise moves immune cells
Why exercise when sick can be risky
Strength vs cardio for immunity
The immune system takeaway everyone needs
📚Books by our ZOE Scientists
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Good Mood Food (preorder) by Prof. Tim Spector
Free resources from ZOE
The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra
Eating for Better Brain Health: Your brain-gut blueprint
Howto eat in 2026- Discover ZOE’s 8 nutrition principles for long-term health
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Mentioned in today's episode
Organ Speak: What it really means to listen to our bodies by Giulia Enders
Associationof Stress-Related Disorders With Autoimmune Disease, JAMA (2018)
Sugar-sweetenedsoda consumption and risk of developing rheumatoid arthritis, AJCN (2014)
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Episode transcripts are available here.