
Healing From Grief & Loss | Dr. Mary-Frances O'Connor
from Huberman Lab
by Scicomm Media
Published: Mon Jun 02 2025
Show Notes
My guest is Dr. Mary-Frances O’Connor, PhD, Professor of Clinical Psychology and Psychiatry at the University of Arizona and a world expert on the science of grief and loss. We discuss what happens in the brain and body when we grieve, the role of dopamine and yearning in the grieving process, the health risks of getting stuck at particular stages of grief and how to move through loss while also deeply honoring the person, animal or thing that is no longer with us. Dr. O’Connor explains that grief involves cycling back and forth between protest and despair (often guilt and anger too) and explains science-supported ways to move through that process in the healthiest possible way. Everyone experiences grief and loss at some point. Dr. O’Connor provides valuable knowledge and tools to help you navigate grief under any circumstance.
Read the episode show notes at hubermanlab.com.
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Timestamps
Mary-Frances O’Connor
Grief vs Grieving; Love & Bonding, Gone Yet Everlasting
Sponsors: Wealthfront & BetterHelp
Sudden vs Slow Death, Attachment, Reframing Relationship
Religion, Integrating the New Relationship
Yearning, Dopamine, Brain, Addiction
Culture & Grief Literacy; Protest, Despair & Hope, New Relationships
Sponsors: AG1 & Helix Sleep
Protest, Despair & Transmutation; Changing Attachment Hierarchy
Bereavement Support, Medical Risk
Culture, Alcohol & Death; Dying of a Broken Heart, Medical Risk
Sponsor: Function
Navigating Grief, Emotions & Body, Tool: Progressive Muscle Relaxation
Grief Stages; Permission & Coping, Judgment & Guilt; Lessons from Grief
Grieving Suicide, Rumination, Tool: Shifting Environment
Belief Systems, Religion & Grief
Afterlife, Contemplating Death
Tools: Contemplating Death; Life Celebration, Terror Management, Empathy
Mental Oscillation, Dual Model of Bereavement
Avoidance; Remembering a Loved One, Resilience; Getting Worse & Seeking Professional Help
Time Perception & End of Life, Motivation & Energy
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