Podcst
Essentials: How to Control Your Sense of Pain & Pleasure by Scicomm Media

Essentials: How to Control Your Sense of Pain & Pleasure

from Huberman Lab

by Scicomm Media

Published: Thu Jun 19 2025

Show Notes

In this Huberman Lab Essentials episode, I explore the sensations of pain and pleasure, explaining how they are sensed in the body and interpreted by the brain as well as methods to control their intensity.

I discuss both the hardwired mechanisms and subjective factors that shape an individual’s perception of pain and pleasure. I also explain why pain thresholds vary from person to person and discuss various treatments for pain management such as acupuncture and supplements. Finally, I explain the role of key neurochemicals like dopamine and serotonin in mediating our experience of pain and pleasure.

Read the episode show notes at hubermanlab.com.

Thank you to our sponsors

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Timestamps

Pain & Pleasure

Skin, Appetitive vs Aversive Behaviors

Skin, Neurons & Brain

Brain Interpretation, Homunculus, Two-Point Discrimination Test

Pain & Pleasure, Subjective Interpretation

Sponsor: AG1

Tool: Pain & Expectation

Pain Threshold

Heat & Cold, Tool: Moving into Cold or Hot Environments

Subjective Pain, Psychosomatic, Fibromyalgia, Whole Body Pain, Acetyl-L-carnitine

Acupuncture, Electroacupuncture, Pain Management

Sponsors: LMNT & Eight Sleep

Red Heads & Pain Threshold, Endorphins

Improving Pain Threshold, Dopamine

Pleasure, Dopamine, Serotonin; Depression, Anti-depressants

Pleasure & Pain Balance, Dopamine, Addiction

Recap & Key Takeaways

Disclaimer & Disclosures

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