
Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg
from Huberman Lab
by Scicomm Media
Published: Thu Dec 11 2025
Show Notes
In this Huberman Lab Essentials episode, my guest is Dr. Justin Sonnenburg, PhD, a professor of microbiology and immunology at Stanford University.
We discuss how microbes in our gut impact our mental and physical health and how diet and the environment affect the gut microbiome. We explain how lifestyle factors such as antibiotics and Western-style diets (high fat, low fiber and rich in processed foods) can damage gut diversity and whether prebiotics or probiotics are useful tools. Throughout the episode, we highlight evidence-based dietary and lifestyle strategies for improving gut health.
Episode show notes: https://go.hubermanlab.com/VXfckJf
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Timestamps
Justin Sonnenburg
What is the Microbiome?
Microbiome Origin, Babies, Environmental Factors
Healthy Microbiome, Individuality; Industrialized vs Traditional Populations
Sponsor: AG1
“Reprogramming” the Gut Microbiome; Antibiotics, Western Diet
Cleanses & Fasting
Processed Foods & Microbiome, Artificial Sweeteners, Emulsifiers
Sponsor: Joovv
Inflammatory Western Diseases, Microbiome & Immune System
Fiber, Fermented Foods & Microbiome, Tool: Fermented Food Consumption
Sponsor: Function
Fiber, Depleted Microbiome, Industrialization, Sanitation
Antibiotics, Over-Sanitation, Disease, Hand Washing
Probiotics, Tool: Product Validation,
Prebiotics, Tool: Plant Consumption
Good Gut Book, Justin’s Research
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